About us

Welcome to Mississippi County Hospital System

Mississippi County Hospital System operates Great River Medical Center in Blytheville and SMC Regional Medical Center in Osceola, serving patients throughout Mississippi County and the surrounding region. Great River Medical Center is an acute care hospital providing emergency care, medical and surgical services, women’s health services, diagnostic care, and other hospital-based services. SMC Regional Medical Center operates as a Rural Emergency Hospital, providing 24/7 emergency care, observation services, diagnostic services, and additional outpatient care.

Mississippi County Hospital System

MCHS operates Great River Medical Center, an acute care hospital offering general medical, surgical, and emergency room services in Blytheville, Arkansas, and SMC Regional Medical Center, a Rural Emergency Hospital in Osceola, Arkansas.